![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Vol. 12, Issue 2, 449-462, February 2001
*Molecular and Structural Neurobiology and Gene Therapy Program,
State University of New York, Buffalo, New York 14214; Arizona State
University, Tempe, Arizona 85287; In bovine adrenal medullary cells synergistically acting
type 1 and type 2 angiotensin II (AII) receptors activate the
fibroblast growth factor-2 (FGF-2) gene through a unique AII-responsive
promoter element. Both the type 1 and type 2 AII receptors and
the downstream cyclic adenosine 1',3'-monophosphate- and protein kinase
C-dependent signaling pathways activate the FGF-2 promoter through a
novel signal-transducing mechanism. This mechanism, which we have named integrative nuclear FGF receptor-1 signaling, involves the nuclear translocation of FGF receptor-1 and its subsequent transactivation of
the AII-responsive element in the FGF-2 promoter.
The Scripps Research
Institute, La Jolla, California 92037; and §University of
Pennsylvania, Schools of Medicine and Veterinary Medicine,
Philadelphia, Pennsylvania 19104
These authors contributed equally to this work.
Present address: Biosignaling Department, National
Institute of Bioscience and Human Technology, Higashi 1-1, Tsukuba,
Ibaraki 305-8566, Japan.
¶
Corresponding author. E-mail address:
mks4{at}Buffalo.edu.
This article has been cited by other articles:
|
|
 |
|
  J.-L. Lee, M.-J. Wang, and J.-Y. Chen Acetylation and activation of STAT3 mediated by nuclear translocation of CD44 J. Cell Biol., June 15, 2009; 185(6): 949 - 957. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Li, H. Guo, X. Luo, J. Sheng, S. Yang, Y. Yin, J. Zhou, and J. Zhou Apomorphine-induced activation of dopamine receptors modulates FGF-2 expression in astrocytic cultures and promotes survival of dopaminergic neurons FASEB J, June 1, 2006; 20(8): 1263 - 1265. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. M. Dunham-Ems, H. E. Pudavar, J. M. Myers, P. A. Maher, P. N. Prasad, and M. K. Stachowiak Factors Controlling Fibroblast Growth Factor Receptor-1's Cytoplasmic Trafficking and Its Regulation as Revealed by FRAP Analysis Mol. Biol. Cell, May 1, 2006; 17(5): 2223 - 2235. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Giri, M. Ali-Seyed, L.-Y. Li, D.-F. Lee, P. Ling, G. Bartholomeusz, S.-C. Wang, and M.-C. Hung Endosomal Transport of ErbB-2: Mechanism for Nuclear Entry of the Cell Surface Receptor Mol. Cell. Biol., December 15, 2005; 25(24): 11005 - 11018. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Kanehira, T. Tani, T. Takagi, Y. Nakano, E. F. Howard, and M. Tamura Angiotensin II Type 2 Receptor Gene Deficiency Attenuates Susceptibility to Tobacco-Specific Nitrosamine-Induced Lung Tumorigenesis: Involvement of Transforming Growth Factor-{beta}-Dependent Cell Growth Attenuation Cancer Res., September 1, 2005; 65(17): 7660 - 7665. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Bharali, I. Klejbor, E. K. Stachowiak, P. Dutta, I. Roy, N. Kaur, E. J. Bergey, P. N. Prasad, and M. K. Stachowiak Organically modified silica nanoparticles: A nonviral vector for in vivo gene delivery and expression in the brain PNAS, August 9, 2005; 102(32): 11539 - 11544. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Fang, E. K. Stachowiak, S. M. Dunham-Ems, I. Klejbor, and M. K. Stachowiak Control of CREB-binding Protein Signaling by Nuclear Fibroblast Growth Factor Receptor-1: A NOVEL MECHANISM OF GENE REGULATION J. Biol. Chem., August 5, 2005; 280(31): 28451 - 28462. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Kardami, Z.-S. Jiang, S. K Jimenez, C. J Hirst, F. Sheikh, P. Zahradka, and P. A Cattini Fibroblast growth factor 2 isoforms and cardiac hypertrophy Cardiovasc Res, August 15, 2004; 63(3): 458 - 466. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hu, X. Fang, S. M. Dunham, C. Prada, E. K. Stachowiak, and M. K. Stachowiak 90-kDa Ribosomal S6 Kinase Is a Direct Target for the Nuclear Fibroblast Growth Factor Receptor 1 (FGFR1): ROLE IN FGFR1 SIGNALING J. Biol. Chem., July 9, 2004; 279(28): 29325 - 29335. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. E. Mabrouk, Q. N. Diep, K. Benkirane, R. M. Touyz, and E. L. Schiffrin SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension Am J Physiol Heart Circ Physiol, May 1, 2004; 286(5): H1954 - H1962. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Malecki, J. Wesche, C. S. Skjerpen, A. Wiedlocha, and S. Olsnes Translocation of FGF-1 and FGF-2 across Vesicular Membranes Occurs during G1-Phase by a Common Mechanism Mol. Biol. Cell, February 1, 2004; 15(2): 801 - 814. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Claus, F. Doring, S. Gringel, F. Muller-Ostermeyer, J. Fuhlrott, T. Kraft, and C. Grothe Differential Intranuclear Localization of Fibroblast Growth Factor-2 Isoforms and Specific Interaction with the Survival of Motoneuron Protein J. Biol. Chem., January 3, 2003; 278(1): 479 - 485. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Olsnes, O. Klingenberg, and A. Wiedlocha Transport of Exogenous Growth Factors and Cytokines to the Cytosol and to the Nucleus Physiol Rev, January 1, 2003; 83(1): 163 - 182. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Goldfarb Signaling By Fibroblast Growth Factors: The Inside Story Sci. Signal., October 30, 2001; 2001(106): pe37 - pe37. [Abstract] [Full Text] [PDF]
|
|
