Molecular Biology of the Cell track citations

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
 QUICK SEARCH:   [advanced]


     


This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhu, X.
Right arrow Articles by Assoian, R. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhu, X.
Right arrow Articles by Assoian, R. K.

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation [published erratum appears in Mol Biol Cell 1996 Jun;7(6):1001]

X Zhu and RK Assoian

Department of Cell Biology and Anatomy, University of Miami School of Medicine, Florida 33101, USA.

Adhesion to extracellular matrix mediates cell cycle progression in mid- late G1; this effect involves an integrin-dependent organization of the cytoskeleton and a consequent change in cell shape. In an effort to identify potential signal-transducing agents that are associated with integrin-dependent shape changes, we looked for kinase activities that were stimulated by long-term adhesion of G0-synchronized NIH-3T3 cells to fibronectin-coated dishes. Several kinase activities were stimulated by this procedure, two of which migrated at 42 and 44 kDa and phosphorylated myelin basic protein in vitro. Blotting with anti- phosphotyrosine and anti-mitogen-activated protein (MAP) kinase antibodies identified these enzymes as ERK 1 and ERK 2. In contrast to the rapid and transient activation of these MAP kinases by platelet- derived growth factor, stimulation of MAP kinase activity by fibronectin was gradual, persistent, and associated with cell spreading rather than cell attachment itself. Cytochalasin D blocked the activation of MAP kinase activity that was induced by the binding of cells to fibronectin. Moreover, MAP kinase was also activated by adhesion of cells to vitronectin and type IV collagen; these effects were also associated with cell spreading. These results distinguish the regulation of G1 phase MAP kinase activity by soluble mitogens and extracellular matrix. They also implicate MAP kinase in shape-dependent cell cycle progression.

Volume 6, Issue 3, pp. 273-282, 03/01/1995
Copyright © 1995 by The American Society for Cell Biology




This article has been cited by other articles:


Home page
J. Biol. Chem.Home page
F. C. Gushiken, V. Patel, Y. Liu, S. Pradhan, A. L. Bergeron, Y. Peng, and K. V. Vijayan
Protein Phosphatase 2A Negatively Regulates Integrin {alpha}IIb{beta}3 Signaling
J. Biol. Chem., May 9, 2008; 283(19): 12862 - 12869.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
D. Finlay and K. Vuori
Novel Noncatalytic Role for Caspase-8 in Promoting Src-Mediated Adhesion and Erk Signaling in Neuroblastoma Cells
Cancer Res., December 15, 2007; 67(24): 11704 - 11711.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
T. Hayashida, M.-H. Wu, A. Pierce, A.-C. Poncelet, J. Varga, and H. W. Schnaper
MAP-kinase activity necessary for TGFbeta1-stimulated mesangial cell type I collagen expression requires adhesion-dependent phosphorylation of FAK tyrosine 397
J. Cell Sci., December 1, 2007; 120(23): 4230 - 4240.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
J. V. Welser, N. Lange, C. A. Singer, M. Elorza, P. Scowen, K. D. Keef, W. T. Gerthoffer, and D. J. Burkin
Loss of the {alpha}7 Integrin Promotes Extracellular Signal-Regulated Kinase Activation and Altered Vascular Remodeling
Circ. Res., September 28, 2007; 101(7): 672 - 681.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
V. H. Fan, A. Au, K. Tamama, R. Littrell, L. B. Richardson, J. W. Wright, A. Wells, and L. G. Griffith
Tethered Epidermal Growth Factor Provides a Survival Advantage to Mesenchymal Stem Cells
Stem Cells, May 1, 2007; 25(5): 1241 - 1251.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
R. G. Jones, X. Li, P. D. Gray, J. Kuang, F. Clayton, W. S. Samowitz, B. B. Madison, D. L. Gumucio, and S. K. Kuwada
Conditional deletion of {beta}1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality
J. Cell Biol., November 6, 2006; 175(3): 505 - 514.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
S. Osmanagic-Myers, M. Gregor, G. Walko, G. Burgstaller, S. Reipert, and G. Wiche
Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration
J. Cell Biol., August 14, 2006; 174(4): 557 - 568.
[Abstract] [Full Text] [PDF]


Home page
Exp. Biol. Med.Home page
K. V. Vijayan and P. F. Bray
Molecular Mechanisms of Prothrombotic Risk Due to Genetic Variations in Platelet Genes: Enhanced Outside-In Signaling Through the Pro33 Variant of Integrin {beta}3.
Experimental Biology and Medicine, May 1, 2006; 231(5): 505 - 513.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
J. Fassett, D. Tobolt, and L. K. Hansen
Type I Collagen Structure Regulates Cell Morphology and EGF Signaling in Primary Rat Hepatocytes through cAMP-dependent Protein Kinase A
Mol. Biol. Cell, January 1, 2006; 17(1): 345 - 356.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. J. Wall, E. Werner, Z. Werb, and Y. A. DeClerck
Discoidin Domain Receptor 2 Mediates Tumor Cell Cycle Arrest Induced by Fibrillar Collagen
J. Biol. Chem., December 2, 2005; 280(48): 40187 - 40194.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
K. D. McClure and G. Schubiger
Developmental analysis and squamous morphogenesis of the peripodial epithelium in Drosophila imaginal discs
Development, November 15, 2005; 132(22): 5033 - 5042.
[Abstract] [Full Text] [PDF]


Home page
Nephrol Dial TransplantHome page
K. Kanegae, M. Tamura, N. Kabashima, R. Serino, M. Tokunaga, S. Oikawa, and Y. Nakashima
Synergistic induction of monocyte chemoattractant protein-1 by integrins and platelet-derived growth factor via focal adhesion kinase in mesangial cells
Nephrol. Dial. Transplant., October 1, 2005; 20(10): 2080 - 2088.
[Abstract] [Full Text] [PDF]


Home page
Biophys. JHome page
C. A. Reinhart-King, M. Dembo, and D. A. Hammer
The Dynamics and Mechanics of Endothelial Cell Spreading
Biophys. J., July 1, 2005; 89(1): 676 - 689.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. V. Vijayan, Y. Liu, W. Sun, M. Ito, and P. F. Bray
The Pro33 Isoform of Integrin {beta}3 Enhances Outside-in Signaling in Human Platelets by Regulating the Activation of Serine/Threonine Phosphatases
J. Biol. Chem., June 10, 2005; 280(23): 21756 - 21762.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
C.-H. Wong, W. Xia, N. P. Y. Lee, D. D. Mruk, W. M. Lee, and C. Y. Cheng
Regulation of Ectoplasmic Specialization Dynamics in the Seminiferous Epithelium by Focal Adhesion-Associated Proteins in Testosterone-Suppressed Rat Testes
Endocrinology, March 1, 2005; 146(3): 1192 - 1204.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
S. J. Kim, J. H. Park, J. E. Lee, J. M. Kim, J. B. Lee, S. Y. Moon, S. I. Roh, C. G. Kim, and H. S. Yoon
Effects of Type IV Collagen and Laminin on the Cryopreservation of Human Embryonic Stem Cells
Stem Cells, November 1, 2004; 22(6): 950 - 961.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
P. Villalonga, R. M. Guasch, K. Riento, and A. J. Ridley
RhoE Inhibits Cell Cycle Progression and Ras-Induced Transformation
Mol. Cell. Biol., September 15, 2004; 24(18): 7829 - 7840.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. Mitsushima, A. Suwa, T. Amachi, K. Ueda, and N. Kioka
Extracellular Signal-regulated Kinase Activated by Epidermal Growth Factor and Cell Adhesion Interacts with and Phosphorylates Vinexin
J. Biol. Chem., August 13, 2004; 279(33): 34570 - 34577.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. Chen, A. J. Koh, N. S. Datta, J. Zhang, E. T. Keller, G. Xiao, R. T. Franceschi, N. J. D'Silva, and L. K. McCauley
Impact of the Mitogen-activated Protein Kinase Pathway on Parathyroid Hormone-related Protein Actions in Osteoblasts
J. Biol. Chem., July 9, 2004; 279(28): 29121 - 29129.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Renal Physiol.Home page
S. Zhougang and R. G. Schnellmann
H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells
Am J Physiol Renal Physiol, May 1, 2004; 286(5): F858 - F865.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Denti, A. Sirri, A. Cheli, L. Rogge, G. Innamorati, S. Putignano, M. Fabbri, R. Pardi, and E. Bianchi
RanBPM Is a Phosphoprotein That Associates with the Plasma Membrane and Interacts with the Integrin LFA-1
J. Biol. Chem., March 26, 2004; 279(13): 13027 - 13034.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
V. Pons, C. Peres, J.-M. Teulie, M. Nauze, M. Mus, C. Rolland, X. Collet, B. Perret, A. Gassama-Diagne, and F. Hullin-Matsuda
Enterophilin-1 Interacts with Focal Adhesion Kinase and Decreases {beta}1 Integrins in Intestinal Caco-2 Cells
J. Biol. Chem., March 5, 2004; 279(10): 9270 - 9277.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
C. M. Nelson and C. S. Chen
VE-cadherin simultaneously stimulates and inhibits cell proliferation by altering cytoskeletal structure and tension
J. Cell Sci., September 1, 2003; 116(17): 3571 - 3581.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
B. S. Zuckerbraun, R. A. Shapiro, T. R. Billiar, and E. Tzeng
RhoA Influences the Nuclear Localization of Extracellular Signal-Regulated Kinases to Modulate p21Waf/Cip1 Expression
Circulation, August 19, 2003; 108(7): 876 - 881.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
L. Neff, M. Zeisel, V. Druet, K. Takeda, J.-P. Klein, J. Sibilia, and D. Wachsmann
ERK 1/2- and JNKs-dependent Synthesis of Interleukins 6 and 8 by Fibroblast-like Synoviocytes Stimulated with Protein I/II, a Modulin from Oral Streptococci, Requires Focal Adhesion Kinase
J. Biol. Chem., July 18, 2003; 278(30): 27721 - 27728.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. V. Vijayan, Y. Liu, J.-F. Dong, and P. F. Bray
Enhanced Activation of Mitogen-activated Protein Kinase and Myosin Light Chain Kinase by the Pro33 Polymorphism of Integrin beta 3
J. Biol. Chem., January 31, 2003; 278(6): 3860 - 3867.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
H. Liao, R. Bucala, and R. A. Mitchell
Adhesion-dependent Signaling by Macrophage Migration Inhibitory Factor (MIF)
J. Biol. Chem., January 3, 2003; 278(1): 76 - 81.
[Abstract] [Full Text] [PDF]


Home page
Crit. Rev. Oral Biol. Med.Home page
W. J. Grzesik and A.S. Narayanan
CEMENTUM AND PERIODONTAL WOUND HEALING AND REGENERATION
Crit. Rev. Oral. Biol. Med., November 1, 2002; 13(6): 474 - 484.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
M. M. Monick, L. Powers, N. Butler, T. Yarovinsky, and G. W. Hunninghake
Interaction of matrix with integrin receptors is required for optimal LPS-induced MAP kinase activation
Am J Physiol Lung Cell Mol Physiol, August 1, 2002; 283(2): L390 - L402.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
S. Li, P. Butler, Y. Wang, Y. Hu, D. C. Han, S. Usami, J.-L. Guan, and S. Chien
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells
PNAS, March 19, 2002; 99(6): 3546 - 3551.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
W. O. Twal, A. Czirok, B. Hegedus, C. Knaak, M. R. Chintalapudi, H. Okagawa, Y. Sugi, and W. S. Argraves
Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility
J. Cell Sci., March 14, 2002; 114(24): 4587 - 4598.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. Yi, S. Kloeker, C. C. Jensen, S. Bockholt, H. Honda, H. Hirai, and M. C. Beckerle
Members of the Zyxin Family of LIM Proteins Interact with Members of the p130Cas Family of Signal Transducers
J. Biol. Chem., March 8, 2002; 277(11): 9580 - 9589.
[Abstract] [Full Text] [PDF]


Home page
Cell Growth Differ.Home page
T. L. Davis, F. Buerger, and A. E. Cress
Differential Regulation of a Novel Variant of the {alpha}6 Integrin, {alpha}6p
Cell Growth Differ., March 1, 2002; 13(3): 107 - 113.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. Chen, C. Baskerville, Q. Han, Z. K. Pan, and S. Huang
alpha v Integrin, p38 Mitogen-activated Protein Kinase, and Urokinase Plasminogen Activator Are Functionally Linked in Invasive Breast Cancer Cells
J. Biol. Chem., December 14, 2001; 276(51): 47901 - 47905.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Ishii, E. Satoh, and M. Nishimura
Integrin-linked Kinase Controls Neurite Outgrowth in N1E-115 Neuroblastoma Cells
J. Biol. Chem., November 9, 2001; 276(46): 42994 - 43003.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
A. Datta, Q. Shi, and D. E. Boettiger
Transformation of Chicken Embryo Fibroblasts by v-src Uncouples {beta}1 Integrin-Mediated Outside-in but Not Inside-out Signaling
Mol. Cell. Biol., November 1, 2001; 21(21): 7295 - 7306.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
C. Rescan, A. Coutant, H. Talarmin, N. Theret, D. Glaise, C. Guguen-Guillouzo, and G. Baffet
Mechanism in the Sequential Control of Cell Morphology and S Phase Entry by Epidermal Growth Factor Involves Distinct MEK/ERK Activations
Mol. Biol. Cell, March 1, 2001; 12(3): 725 - 738.
[Abstract] [Full Text]


Home page
Cancer Res.Home page
A. V. Bazarov, S. Adachi, S.-F. Li, M. K. Mateyak, S. Wei, and J. M. Sedivy
A Modest Reduction in c-Myc Expression Has Minimal Effects on Cell Growth and Apoptosis But Dramatically Reduces Susceptibility to Ras and Raf Transformation
Cancer Res., February 1, 2001; 61(3): 1178 - 1186.
[Abstract] [Full Text]


Home page
J. Cell Biol.Home page
I. Nakamura, L. Lipfert, G. A. Rodan, and Le T. Duong
Convergence of {{alpha}}v{beta}3 Integrin- and Macrophage Colony Stimulating Factor-mediated Signals on Phospholipase C{{gamma}} in Prefusion Osteoclasts
J. Cell Biol., January 22, 2001; 152(2): 361 - 374.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
S. M. Kutz, J. Hordines, P. J. McKeown-Longo, and P. J. Higgins
TGF-{beta}1-induced PAI-1 gene expression requires MEK activity and cell-to-substrate adhesion
J. Cell Sci., January 11, 2001; 114(21): 3905 - 3914.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
E. H.J. Danen, P. Sonneveld, A. Sonnenberg, and K. M. Yamada
Dual Stimulation of Ras/Mitogen-activated Protein Kinase and RhoA by Cell Adhesion to Fibronectin Supports Growth Factor-stimulated Cell Cycle Progression
J. Cell Biol., December 18, 2000; 151(7): 1413 - 1422.
[Abstract] [Full Text] [PDF]


Home page
FASEB J.Home page
M. G. WILKINSON and J. B. A. MILLAR
Control of the eukaryotic cell cycle by MAP kinase signaling pathways
FASEB J, November 1, 2000; 14(14): 2147 - 2157.
[Abstract] [Full Text]


Home page
HypertensionHome page
K. Matrougui, Y. E. G. Eskildsen-Helmond, A. Fiebeler, D. Henrion, B. I. Levy, A. Tedgui, and M. J. Mulvany
Angiotensin II Stimulates Extracellular Signal-Regulated Kinase Activity in Intact Pressurized Rat Mesenteric Resistance Arteries
Hypertension, October 1, 2000; 36(4): 617 - 621.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
P. R. Chess, L. Toia, and J. N. Finkelstein
Mechanical strain-induced proliferation and signaling in pulmonary epithelial H441 cells
Am J Physiol Lung Cell Mol Physiol, July 1, 2000; 279(1): L43 - L51.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
S. K. Kuwada and X. Li
Integrin alpha 5/beta 1 Mediates Fibronectin-dependent Epithelial Cell Proliferation through Epidermal Growth Factor Receptor Activation
Mol. Biol. Cell, July 1, 2000; 11(7): 2485 - 2496.
[Abstract] [Full Text]


Home page
Am. J. Physiol. Gastrointest. Liver Physiol.Home page
C. F. Yu, M. A. Sanders, and M. D. Basson
Human Caco-2 motility redistributes FAK and paxillin and activates p38 MAPK in a matrix-dependent manner
Am J Physiol Gastrointest Liver Physiol, June 1, 2000; 278(6): G952 - G966.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
H. Rosenfeldt and F. Grinnell
Fibroblast Quiescence and the Disruption of ERK Signaling in Mechanically Unloaded Collagen Matrices
J. Biol. Chem., February 4, 2000; 275(5): 3088 - 3092.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
M. W. Renshaw, L. S. Price, and M. A. Schwartz
Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of MAP Kinase
J. Cell Biol., November 1, 1999; 147(3): 611 - 618.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. E. Aplin, S. M. Short, and R. L. Juliano
Anchorage-dependent Regulation of the Mitogen-activated Protein Kinase Cascade by Growth Factors Is Supported by a Variety of Integrin alpha Chains
J. Biol. Chem., October 29, 1999; 274(44): 31223 - 31228.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
K. Roovers, G. Davey, X. Zhu, M. E. Bottazzi, and R. K. Assoian
alpha 5beta 1 Integrin Controls Cyclin D1 Expression by Sustaining Mitogen-activated Protein Kinase Activity in Growth Factor-treated Cells
Mol. Biol. Cell, October 1, 1999; 10(10): 3197 - 3204.
[Abstract] [Full Text]


Home page
Mol. Biol. CellHome page
M. F. Brizzi, P. Defilippi, A. Rosso, M. Venturino, G. Garbarino, A. Miyajima, L. Silengo, G. Tarone, and L. Pegoraro
Integrin-mediated Adhesion of Endothelial Cells Induces JAK2 and STAT5A Activation: Role in the Control of c-fos Gene Expression
Mol. Biol. Cell, October 1, 1999; 10(10): 3463 - 3471.
[Abstract] [Full Text]


Home page
J. Cell Biol.Home page
M. E. Bottazzi, X. Zhu, R. M. Bohmer, and R. K. Assoian
Regulation of p21cip1 Expression by Growth Factors and the Extracellular Matrix Reveals a Role for Transient ERK Activity in G1 Phase
J. Cell Biol., September 20, 1999; 146(6): 1255 - 1264.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. R. Asthagiri, C. M. Nelson, A. F. Horwitz, and D. A. Lauffenburger
Quantitative Relationship among Integrin-Ligand Binding, Adhesion, and Signaling via Focal Adhesion Kinase and Extracellular Signal-regulated Kinase 2
J. Biol. Chem., September 17, 1999; 274(38): 27119 - 27127.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
P. J. Keely, E. V. Rusyn, A. D. Cox, and L. V. Parise
R-Ras Signals through Specific Integrin alpha  Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells
J. Cell Biol., May 31, 1999; 145(5): 1077 - 1088.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
J. Geginat, G. Bossi, J. R. Bender, and R. Pardi
Anchorage Dependence of Mitogen-Induced G1 to S Transition in Primary T Lymphocytes
J. Immunol., May 1, 1999; 162(9): 5085 - 5093.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
S. K. Sastry, M. Lakonishok, S. Wu, T. Q. Truong, A. Huttenlocher, C. E. Turner, and A. F. Horwitz
Quantitative Changes in Integrin and Focal Adhesion Signaling Regulate Myoblast Cell Cycle Withdrawal
J. Cell Biol., March 22, 1999; 144(6): 1295 - 1309.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
M. D. Martin-Bermudo and N. H. Brown
Uncoupling integrin adhesion and signaling: the beta PS cytoplasmic domain is sufficient to regulate gene expression in the Drosophila embryo
Genes & Dev., March 15, 1999; 13(6): 729 - 739.
[Abstract] [Full Text]


Home page
J. Biol. Chem.Home page
R.-i. Manabe, N. Oh-e, and K. Sekiguchi
Alternatively Spliced EDA Segment Regulates Fibronectin-dependent Cell Cycle Progression and Mitogenic Signal Transduction
J. Biol. Chem., February 26, 1999; 274(9): 5919 - 5924.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. J. Garton and N. K. Tonks
Regulation of Fibroblast Motility by the Protein Tyrosine Phosphatase PTP-PEST
J. Biol. Chem., February 5, 1999; 274(6): 3811 - 3818.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
G Davey, M Buzzai, and R. Assoian
Reduced expression of (alpha)5(beta)1 integrin prevents spreading-dependent cell proliferation
J. Cell Sci., January 12, 1999; 112(24): 4663 - 4672.
[Abstract] [PDF]


Home page
DevelopmentHome page
Y Yang, N. Relan, D. Przywara, and L Schuger
Embryonic mesenchymal cells share the potential for smooth muscle differentiation: myogenesis is controlled by the cell's shape
Development, January 7, 1999; 126(13): 3027 - 3033.
[Abstract] [PDF]


Home page
J. Cell Sci.Home page
P. Jones, F. Jones, B Zhou, and M Rabinovitch
Induction of vascular smooth muscle cell tenascin-C gene expression by denatured type I collagen is dependent upon a beta3 integrin-mediated mitogen-activated protein kinase pathway and a 122-base pair promoter element
J. Cell Sci., January 2, 1999; 112(4): 435 - 445.
[Abstract] [PDF]


Home page