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Table 1. Overlap between the micropexophagy genes in Picha pastoris and the macroautophagy genes in Saccharomyces cerevisiae


Pichia

Saccharomyces

Unified namea

Reference

Necessary for macroautohagy
    PAZ1/GSA10 APG1 ATG1 (Stromhaug et al., 2001; Mukaiyama et al., 2002)
    PAZ2 AUT7/APG8 ATG8 (Mukaiyama et al., 2002)
    PAZ3 APG16 ATG16 (Mukaiyama et al., 2002)
    PAZ8 AUT2/APG4 ATG4 (Mukaiyama et al., 2002)
    PAZ9/GSA14 APG9 ATG9 (Stromhaug et al., 2001; Mukaiyama et al., 2002)
    GSA7/PAZ12 APG7/CVT2 ATG7 (Yuan et al., 1999; Mukaiyama et al., 2002)
    GSA11/PAZ7 APG2 ATG2 (Stromhaug et al., 2001; Mukaiyama et al., 2002)
    GSA12 AUT10/CVT18 ATG18 (Stromhaug et al., 2001)
    GSA20 AUT1/APG3 ATG3 (Stromhaug et al., 2001)
Necessary for the CVT pathway but not for macroautophagy
    GSA9/PAZ6 CVT9 ATG11 (Kim et al., 2001; Mukaiyama et al., 2002)
Necessary for pexophagy but not for macroautophagy or Cvt pathway
    PAZ4

UGT51

ATG26

(Oku et al., 2003)

a Recently, autophagy-related genes from several yeast species have been unified as ATG genes. See "Note added in proof" for unified nomenclature of genes.





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