A Functional Relationship between NuMA and Kid Is Involved in Both Spindle Organization and Chromosome Alignment in Vertebrate Cells
Mol. Biol. Cell
Levesque et al. 10.1091/mbc.E03-02-0082.
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Time-lapse video microscopy reveals chromosome movement at normal velocities in a human CFPAC-1 cell injected with antibodies to both Kid and NuMA. These and other data show that chromosomes interact with spindle microtubules appropriately following injection with antibodies to both Kid and NuMA, however, they do not align at the spindle equator.
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