Supplemental Figure

This article contains the following supporting material:

• Supplemental Figure.pdf - Effect of paraquat on lysosomal stability. Lysosomes isolated from livers of untreated rats or rats treated with 40mg/kg body weight or 80mg/kg body weight paraquat, as labeled, were incubated in an isotonic buffer at 37 °C. At different times the release of β-hexosaminidase into the incubation medium was measured by standard fluorometric procedures. Values are expressed as percentage of total activity in the lysosomal fraction and are mean + S.E. for 3 different experiments. Note that the higher doses of paraquat, but not the lower one (used through this work), results in increased release of the enzyme both right after isolation (time 0) and during the incubation at 37 °C.

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