Supplemental Material

This article contains the following supporting material:

• Figure 1 - Identification of a more potent congener of salubrinal. (A) Chemical structure of salubrinal and Sal003. (B) Induction of eIF2α phoshorylation by salubrinal and Sal003. MEFs were incubated with salubrinal or Sal003 for 12 h at the indicated concentrations. After preparation of extracts, levels of phospho-eIF2α and total eIF2α were determined by western blotting.