QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: E02-07-0438v1 13/12/4111    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Macara, I. G. Articles by Zieger, B. Search for Related Content PubMed PubMed Citation Articles by Macara, I. G. Articles by Zieger, B.

Vol. 13, Issue 12, 4111-4113, December 2002

ESSAY
Mammalian Septins Nomenclature

Ian G. Macara,^* Richard Baldarelli, Christine M. Field,^§ Michael Glotzer, Yasuhide Hayashi,^¶ Shu-Chan Hsu,^# Mary B. Kennedy,^@ Makoto Kinoshita,^§ Mark Longtine,^** Claudia Low, Lois J. Maltais, Louise McKenzie, Timothy J. Mitchison,^§ Toru Nishikawa, Makoto Noda,^§§ Elizabeth M. Petty, Mark Peifer,^¶¶ John R. Pringle,^¶¶ Phillip J. Robinson,^## Dagmar Roth,^@@ S.E. Hilary Russell,^*** Heidi Stuhlmann, Manami Tanaka, Tomoo Tanaka,^§§§ William S. Trimble, Jerry Ware,^¶¶¶ Nancy J. Zeleznik-Le,^### and Barbara Zieger^@@@

 ^*Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908;  Mouse Genome Informatics, Jackson Laboratories, Bar Harbor, Maine 04609;  ^§Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115;  Research Institute of Molecular Pathology, A-1030 Vienna, Austria;  ^¶Department of Pediatrics, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan;  ^#Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854;  ^@Division of Biology, California Institute of Technology, Pasadena, California 91125;  ^**Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078;  Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, Virginia 22908;  Section of Psychiatry and Behavioral Sciences, Tokyo Medical and Dental University Graduate School, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8519, Japan;  ^§§Department of Molecular Oncology, Kyoto University Graduate School of Medicine, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan;  Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109;  ^¶¶Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599;  ^##Cell Signaling Unit, Children's Medical Research Institute, Wentworthville 2145, New South Wales, Australia;  ^@@Max-Planck-Institute for Brain Research, Department of Neurochemistry, Frankfurt, and Covidence GmbH, Philipp-Helfmann-Strasse 18, D-65760 Eschborn, Germany;  ^***Department of Oncology, Queen's University of Belfast, Belfast BT9 7AB, United Kingdom;  Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, New York 10029;  National Institute of Advanced Industrial Science and Technology, Bldg. Tsukuba Central 6, Higashi, Tsukuba Science City, Ibaraki 305-8566, Japan;  ^§§§Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan;  Program in Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada;  ^¶¶¶The Scripps Research Institute, La Jolla, California 92037;  ^###Cardinal Bernardin Cancer Center and Department of Medicine, Loyola University Medical, Center, Maywood, Illinois 60153; and  ^@@@Department of Pediatrics and Adolescent Medicine, Children's Hospital, University of Freiburg, D-79106 Freiburg, Germany

There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.

---

Corresponding author. E-mail address: igm9c{at}virginia.edu.

---

Molecular Biology of the Cell
Vol. 13, 4111-4113, December 2002
Copyright © 2002 by The American Society for Cell Biology

This article has been cited by other articles:

				M. Zhu, F. Wang, F. Yan, P. Y. Yao, J. Du, X. Gao, X. Wang, Q. Wu, T. Ward, J. Li, et al. Septin 7 Interacts with Centromere-associated Protein E and Is Required for Its Kinetochore Localization J. Biol. Chem., July 4, 2008; 283(27): 18916 - 18925. [Abstract] [Full Text] [PDF]

				N. D. Amin, Y.-L. Zheng, S. Kesavapany, J. Kanungo, T. Guszczynski, R. K. Sihag, P. Rudrabhatla, W. Albers, P. Grant, and H. C. Pant Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis J. Neurosci., April 2, 2008; 28(14): 3631 - 3643. [Abstract] [Full Text] [PDF]

				A. Kalenka, J. Hinkelbein, R. E. Feldmann Jr, W. Kuschinsky, K. F. Waschke, and M. H. Maurer The Effects of Sevoflurane Anesthesia on Rat Brain Proteins: A Proteomic Time-Course Analysis Anesth. Analg., May 1, 2007; 104(5): 1129 - 1135. [Abstract] [Full Text] [PDF]

				C. S. Kim, S. K. Seol, O.-K. Song, J. H. Park, and S. K. Jang An RNA-Binding Protein, hnRNP A1, and a Scaffold Protein, Septin 6, Facilitate Hepatitis C Virus Replication J. Virol., April 15, 2007; 81(8): 3852 - 3865. [Abstract] [Full Text] [PDF]

				M. Taniguchi, M. Taoka, M. Itakura, A. Asada, T. Saito, M. Kinoshita, M. Takahashi, T. Isobe, and S.-i. Hisanaga Phosphorylation of Adult Type Sept5 (CDCrel-1) by Cyclin-dependent Kinase 5 Inhibits Interaction with Syntaxin-1 J. Biol. Chem., March 16, 2007; 282(11): 7869 - 7876. [Abstract] [Full Text] [PDF]

				H.-O. Park and E. Bi Central Roles of Small GTPases in the Development of Cell Polarity in Yeast and Beyond Microbiol. Mol. Biol. Rev., March 1, 2007; 71(1): 48 - 96. [Abstract] [Full Text] [PDF]

				C. Low and I. G. Macara Structural Analysis of Septin 2, 6, and 7 Complexes J. Biol. Chem., October 13, 2006; 281(41): 30697 - 30706. [Abstract] [Full Text] [PDF]

				S. Amir, R. Wang, H. Matzkin, J. W. Simons, and N. J. Mabjeesh MSF-A Interacts with Hypoxia-Inducible Factor-1{alpha} and Augments Hypoxia-Inducible Factor Transcriptional Activation to Affect Tumorigenicity and Angiogenesis Cancer Res., January 15, 2006; 66(2): 856 - 866. [Abstract] [Full Text] [PDF]

				B. E. Kremer, T. Haystead, and I. G. Macara Mammalian Septins Regulate Microtubule Stability through Interaction with the Microtubule-binding Protein MAP4 Mol. Biol. Cell, October 1, 2005; 16(10): 4648 - 4659. [Abstract] [Full Text] [PDF]

				M. Pache, B. Zieger, S. Blaser, and P. Meyer Immunoreactivity of the Septins SEPT4, SEPT5, and SEPT8 in the Human Eye J. Histochem. Cytochem., September 1, 2005; 53(9): 1139 - 1147. [Abstract] [Full Text] [PDF]

				K.-i. Nagata, T. Asano, Y. Nozawa, and M. Inagaki Biochemical and Cell Biological Analyses of a Mammalian Septin Complex, Sept7/9b/11 J. Biol. Chem., December 31, 2004; 279(53): 55895 - 55904. [Abstract] [Full Text] [PDF]

				C. Martinez and J. Ware Mammalian Septin Function in Hemostasis and Beyond Experimental Biology and Medicine, December 1, 2004; 229(11): 1111 - 1119. [Abstract] [Full Text] [PDF]

				H. An, J. L. Morrell, J. L. Jennings, A. J. Link, and K. L. Gould Requirements of Fission Yeast Septins for Complex Formation, Localization, and Function Mol. Biol. Cell, December 1, 2004; 15(12): 5551 - 5564. [Abstract] [Full Text] [PDF]

				J. L. Morrell, C. B. Nichols, and K. L. Gould The GIN4 family kinase, Cdr2p, acts independently of septins in fission yeast J. Cell Sci., October 15, 2004; 117(22): 5293 - 5302. [Abstract] [Full Text] [PDF]

				K. Kato, C. Martinez, S. Russell, P. Nurden, A. Nurden, S. Fiering, and J. Ware Genetic deletion of mouse platelet glycoprotein Ib{beta} produces a Bernard-Soulier phenotype with increased {alpha}-granule size Blood, October 15, 2004; 104(8): 2339 - 2344. [Abstract] [Full Text] [PDF]

				N. Kinoshita, K. Kimura, N. Matsumoto, M. Watanabe, M. Fukaya, and C. Ide Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes Genes Cells, January 1, 2004; 9(1): 1 - 14. [Abstract] [Full Text] [PDF]

				M. Kinoshita Assembly of Mammalian Septins J. Biochem., October 1, 2003; 134(4): 491 - 496. [Abstract] [Full Text] [PDF]

				J. P. Caviston, M. Longtine, J. R. Pringle, and E. Bi The Role of Cdc42p GTPase-activating Proteins in Assembly of the Septin Ring in Yeast Mol. Biol. Cell, October 1, 2003; 14(10): 4051 - 4066. [Abstract] [Full Text] [PDF]

				M. Ihara, H. Tomimoto, H. Kitayama, Y. Morioka, I. Akiguchi, H. Shibasaki, M. Noda, and M. Kinoshita Association of the Cytoskeletal GTP-binding Protein Sept4/H5 with Cytoplasmic Inclusions Found in Parkinson's Disease and Other Synucleinopathies J. Biol. Chem., June 20, 2003; 278(26): 24095 - 24102. [Abstract] [Full Text] [PDF]

				J. J. Tasto, J. L. Morrell, and K. L. Gould An anillin homologue, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation J. Cell Biol., March 31, 2003; 160(7): 1093 - 1103. [Abstract] [Full Text] [PDF]

				P. J. Sheffield, C. J. Oliver, B. E. Kremer, S. Sheng, Z. Shao, and I. G. Macara Borg/Septin Interactions and the Assembly of Mammalian Septin Heterodimers, Trimers, and Filaments J. Biol. Chem., January 24, 2003; 278(5): 3483 - 3488. [Abstract] [Full Text] [PDF]