![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
|
|
|
|
|
||
A more recent version of this article appeared on November 1, 2002
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Submitted on December 11, 2001
Revised on July 16, 2002
Accepted on July 25, 2002
1 Department of Genetics and Microbiology, Charles University, Vinicná 5, 12844 Prague 2, Czech Republic
2 Laboratoire de Génétique Moléculaire, CNRS 8541, Ecole Normale Supérieure, 46 rue d'Ulm, 75005 Paris, France
3 Department of Genetics and Microbiology, Charles University, Vinic;ná 5, 12844 Prague 2, Czech Republic
* Corresponding author. E-mail address: zdenap{at}natur.cuni.cz.
On solid substrate, growing yeast colonies alternately acidify and alkalinise the medium. Using morphological, cytochemical, genetic and DNA microarray approaches we characterised six temporal steps in the "acid-to-alkali" colony transition. This transition is connected with the production of volatile ammonia acting as starvation signal between colonies. We present evidence that the three membrane proteins Ato1p, Ato2p and Ato3p, members of the YaaH family, are involved in ammonia production in S.cerevisiae colonies. The "acid-to-alkali" transition is connected with decrease of mitochondrial oxidative catabolism and by peroxisome activation, which in parallel with activation of biosynthetic pathways contribute to decrease the general stress level in colonies. These metabolic features characterise a novel survival strategy used by yeast under starvation conditions prevalent in nature.
This article has been cited by other articles:
|
|
 |
|
  K. Gori, H. D. Mortensen, N. Arneborg, and L. Jespersen Ammonia Production and Its Possible Role as a Mediator of Communication for Debaryomyces hansenii and Other Cheese-Relevant Yeast Species J Dairy Sci, November 1, 2007; 90(11): 5032 - 5041. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Reinders, K. Wagner, R. P. Zahedi, D. Stojanovski, B. Eyrich, M. van der Laan, P. Rehling, A. Sickmann, N. Pfanner, and C. Meisinger Profiling Phosphoproteins of Yeast Mitochondria Reveals a Role of Phosphorylation in Assembly of the ATP Synthase Mol. Cell. Proteomics, November 1, 2007; 6(11): 1896 - 1906. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Kim, K. Melen, M. Osterberg, and G. von Heijne A global topology map of the Saccharomyces cerevisiae membrane proteome PNAS, July 25, 2006; 103(30): 11142 - 11147. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Taxis, P. Keller, Z. Kavagiou, L. J. Jensen, J. Colombelli, P. Bork, E. H.K. Stelzer, and M. Knop Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system J. Cell Biol., November 21, 2005; 171(4): 627 - 640. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. P. Tu, A. Kudlicki, M. Rowicka, and S. L. McKnight Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes Science, November 18, 2005; 310(5751): 1152 - 1158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Bourges, S. Horan, and B. Meunier Effect of Inhibition of the bc1 Complex on Gene Expression Profile in Yeast J. Biol. Chem., August 19, 2005; 280(33): 29743 - 29749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Vachova and Z. Palkova Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia J. Cell Biol., June 6, 2005; 169(5): 711 - 717. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Vachova, F. Devaux, H. Kucerova, M. Ricicova, C. Jacq, and Z. Palkova Sok2p Transcription Factor Is Involved in Adaptive Program Relevant for Long Term Survival of Saccharomyces cerevisiae Colonies J. Biol. Chem., September 3, 2004; 279(36): 37973 - 37981. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Guaragnella and R. A. Butow ATO3 Encoding a Putative Outward Ammonium Transporter Is an RTG-independent Retrograde Responsive Gene Regulated by GCN4 and the Ssy1-Ptr3-Ssy5 Amino Acid Sensor System J. Biol. Chem., November 14, 2003; 278(46): 45882 - 45887. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Yaakov, M. Bell, S. Hohmann, and D. Engelberg Combination of Two Activating Mutations in One HOG1 Gene Forms Hyperactive Enzymes That Induce Growth Arrest Mol. Cell. Biol., July 15, 2003; 23(14): 4826 - 4840. [Abstract] [Full Text] [PDF]
|
|
