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A more recent version of this article appeared on December 1, 2002
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Submitted on July 29, 2002
Revised on September 11, 2002
Accepted on September 24, 2002
1 Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
2 Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine 04609, USA
3 Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
4 Research Institute of Molecular Pathology, A-1030 Vienna, Austria
5 Department of Pediatrics, Graduate School of Medicine, University of Tokyo, Tokyo 113-8655, Japan
6 Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA
7 Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
8 Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA
9 Department of Biochemistry, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
10 Section of Psychiatry and Behavioral Sciences, Tokyo Medical and Dental University Graduate School, 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8519, Japan
11 Department of Molecular Oncology, Kyoto University Graduate School of Medicine, Yoshida Konoe-cho, Sakyo-ku, Kyoto, Japan
12 Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
13 Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA
14 Cell Signaling Unit, Children's Medical Research Institute, Wentworthville 2145, New South Wales, Australia
15 Max-Planck-Institute for Brain Research, Department of Neurochemistry, Frankfurt, Germany; and Covidence GmbH, Eschborn, Germany
16 Department of Oncology, Queen's University of Belfast, Belfast BT9 7AB, UK
17 Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, NY 10029, USA
18 National Institute of Advanced Industrial Science and Technology, Bldg. Tsukuba Central 6, Higashi, Tsukuba Science City, Ibaraki 305-8566, Japan
19 Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan
20 Program in Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada
21 The Scripps Research Institute, La Jolla, CA 92037, USA
22 Cardinal Bernardin Cancer Center and Department of Medicine, Loyola University Medical Center, Maywood, IL 60153, USA
23 Children's Hospital, University of Freiburg, D-79106 Freiburg, Germany
* Corresponding author. E-mail address: igm9c{at}virginia.edu.
There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse and Human Genomic Nomenclature Committees (MGNC, HGNC). The human and mouse septin genes will be named SEPT1 - SEPT10 and Sept1 - Sept10, respectively. Splice variants will be designated by an underscore followed by a lower case "v" and a number, e.g., Sept4_v1.
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