![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
|
|
|
|
|
||
A more recent version of this article appeared on December 1, 2004
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Submitted on March 1, 2004
Accepted on September 28, 2004
¶
*Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec, Canada H4P 2R2; ||Department of Biochemistry, McGill University, Montreal, Quebec, Canada H3G 1Y6; Institute of Microbiology, Johann Wolfgang Goethe- University, 60439 Frankfurt am Main, Germany; Molecular Oncology Group, Royal Victoria Hospital, Montreal, Quebec, Canada H3A 1A1
Monitoring Editor: John Pringle
We have determined the transcriptional response of the budding yeast Saccharomyces cerevisiae to cold. Yeast cells were exposed to 10°C for different lengths of time, and DNA microarrays were used to characterize the changes in transcript abundance. Two distinct groups of transcriptionally modulated genes were identified and defined as the early cold response and the late cold response. A detailed comparison of the cold response with various environmental stress responses revealed a substantial overlap between environmental stress response genes and late cold response genes. In addition, the accumulation of the carbohydrate reserves trehalose and glycogen is induced during late cold response. These observations suggest that the environmental stress response (ESR) occurs during the late cold response. The transcriptional activators Msn2p and Msn4p are involved in the induction of genes common to many stress responses and we show that they mediate the stress response pattern observed during the late cold response. In contrast, classical markers of the ESR were absent during the early cold response, and the transcriptional response of the early cold response genes was Msn2p/Msn4p-independent. This implies that the cold-specific early response is mediated by a different and as yet uncharacterized regulatory mechanism.
Corresponding author.
E-mail: babette.schade{at}mcgill.ca
This article has been cited by other articles:
|
|
 |
|
  F. J. Pizarro, M. C. Jewett, J. Nielsen, and E. Agosin Growth Temperature Exerts Differential Physiological and Transcriptional Responses in Laboratory and Wine Strains of Saccharomyces cerevisiae Appl. Envir. Microbiol., October 15, 2008; 74(20): 6358 - 6368. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. L. Tai, P. Daran-Lapujade, M. C. Walsh, J. T. Pronk, and J.-M. Daran Acclimation of Saccharomyces cerevisiae to Low Temperature: A Chemostat-based Transcriptome Analysis Mol. Biol. Cell, December 1, 2007; 18(12): 5100 - 5112. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Sekine, A. Kawaguchi, Y. Hamano, and H. Takagi Desensitization of Feedback Inhibition of the Saccharomyces cerevisiae {gamma}-Glutamyl Kinase Enhances Proline Accumulation and Freezing Tolerance Appl. Envir. Microbiol., June 15, 2007; 73(12): 4011 - 4019. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. L. Tai, P. Daran-Lapujade, M. A. H. Luttik, M. C. Walsh, J. A. Diderich, G. C. Krijger, W. M. van Gulik, J. T. Pronk, and J.-M. Daran Control of the Glycolytic Flux in Saccharomyces cerevisiae Grown at Low Temperature: A MULTI-LEVEL ANALYSIS IN ANAEROBIC CHEMOSTAT CULTURES J. Biol. Chem., April 6, 2007; 282(14): 10243 - 10251. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. W. Owttrim RNA helicases and abiotic stress Nucleic Acids Res., June 21, 2006; 34(11): 3220 - 3230. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Loertscher, L. L. Larson, C. K. Matson, M. L. Parrish, A. Felthauser, A. Sturm, C. Tachibana, M. Bard, and R. Wright Endoplasmic Reticulum-Associated Degradation Is Required for Cold Adaptation and Regulation of Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae Eukaryot. Cell, April 1, 2006; 5(4): 712 - 722. [Abstract] [Full Text] [PDF]
|
|
