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Constitutively active Rac1 (GFP-L61 Rac1, blue) targets to focal adhesions in a mouse embryo fibroblast. Focal adhesions and focal complexes showing Rac1 localization appear fuchsia due to colocalization with antibody-labeled vinculin (red). Phalloidin-labeled F-actin appears green. The activation state of Rac1 regulates its localization to focal adhesions. See the full article by Chang et al. on p. 253 of this issue of MBC. (Image: Fumin Chang and Lew Romer, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine)

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